Debian Med Project
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Summary
Imaging
Debian Med imaging packages

This metapackage will install Debian packages which might be useful in medical image processing.

It installs several packages supporting DICOM (Digital Imaging and Communications in Medicine) which is the de-facto standard for medical image management. The standard defines data structures and services for the exchange of medical images and related information. The latest release has been published in 2008 and consists of 18 parts.

For more information, you can visit the NEMA homepage http://medical.nema.org/ .

The status of the official DICOM base standard plus all the supplements and correction items are summarized at David Clunie's webpage: http://www.dclunie.com/dicom-status/status.html where you'll find direct links to the most recent yearly edition ftp://medical.nema.org/medical/dicom/2008/ .

The list to the right includes various software projects which are of some interest to the Debian Med Project. Currently, only a few of them are available as Debian packages. It is our goal, however, to include all software in Debian Med which can sensibly add to a high quality Debian Pure Blend.

For a better overview of the project's availability as a Debian package, each head row has a color code according to this scheme:

If you discover a project which looks like a good candidate for Debian Med to you, or if you have prepared an unofficial Debian package, please do not hesitate to send a description of that project to the Debian Med mailing list

Links to other tasks

Debian Med Imaging packages

Official Debian packages with high relevance

Aeskulap
medical image viewer and DICOM network client
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Aeskulap is able to load a series of special images stored in the DICOM format for review. Additionally it is able to query and fetch DICOM images from archive nodes (also called PACS) over the network. Aeskulap tries to achieve a full open source replacement for commercially available DICOM viewers.

Screenshots of package aeskulap
Amide
software for Medical Imaging
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AMIDE: (Amide's a Medical Imaging Data Examiner) AMIDE is a tool for viewing and analyzing medical image data sets. It's capabilities include the simultaneous handling of multiple data sets imported from a variety of file formats, image fusion, 3D region of interest drawing and analysis, volume rendering, and rigid body alignments.

Please cite: Andreas Markus Loening and Sanjiv Sam Gambhir: AMIDE: A Free Software Tool for Multimodality Medical Image Analysis. (PubMed) Molecular Imaging 2(3):131-7 (2003)
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Ants
advanced normalization tools for brain and image analysis
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Advanced Normalization Tools (ANTS) is an ITK-based suite of normalization, segmentation and template-building tools for quantitative morphometric analysis. Many of the ANTS registration tools are diffeomorphic, but deformation (elastic and BSpline) transformations are available. Unique components of ANTS include multivariate similarity metrics, landmark guidance, the ability to use label images to guide the mapping and both greedy and space-time optimal implementations of diffeomorphisms. The symmetric normalization (SyN) strategy is a part of the ANTS toolkit as is directly manipulated free form deformation (DMFFD).

This package provides environment-modules configuration. Use 'module load ants' to make all cmdline tools available in your shell.

Please cite: Brian B. Avants, Paul Yushkevich, John Pluta, David Minkoff, Marc Korczykowski, John Detre and James C. Gee: The optimal template effect in hippocampus studies of diseased populations. (2010)
Biosig-tools
format conversion tools for biomedical data formats
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Based on BioSig library, this package provides command line tools, such as

  • save2gdf: converter between different file formats, including but not limited to SCP-ECG(EN1064), HL7aECG (FDA-XML), GDF, EDF, BDF, CWFB. save2gdf can be also used to upload or retrieve data from a bscs server.
Please cite: Alois Schlögl and Clemens Brunner: BioSig: A Free and Open Source Software Library for BCI Research. (eprint) Computer 41(10):44-50 (2008)
Camitk-imp
workbench application for the CamiTK library
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CamiTK helps researchers and clinicians to easily and rapidly collaborate in order to prototype CAMI applications, that feature medical images, surgical navigation and biomechanical simulations.

camitk-imp is the CamiTK workbench application where you can test all available extensions for prototyping. It provides an easy and interactive access to all available data and algorithm parameters, including the one you build yourself using the CamiTK SDK.

For example, camitk-imp can visualize medical images from a lot of different (standard) formats, offers image processing and segmentation algorithms to reconstruct a mesh geometry and run a biomechanical simulation.

Please cite: Céline Fouard, Aurélien Deram, Yannick Keraval and Emmanuel Promayon: CamiTK: a Modular Framework Integrating Visualization, Image Processing and Biomechanical Modeling. :323-354 (2012)
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Caret
Computerized Anatomical Reconstruction and Editing Toolkit
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This software allows for creating, viewing and manipulating surface reconstructions of the cerebral and cerebellar cortex, viewing volumes and for displaying experimental data on the surfaces and volumes. While Caret is primarily a GUI application with 'caret_command' there is also a versatile command line tool, that allows access to a substantial proportion of Caret's functionality.

Caret can download and use stereotaxic atlases (human, monkey, mouse and rat) from an open online database.

Some functionality of Caret is only available when additional data files, provided by the caret-data package, are available. This includes:

  • Map volumes to surface via PALS atlas
  • Multi-resolution morphing
  • Projection of foci via PALS atlas
  • Surface-based registration
  • Surface flattening

Currently the caret-data package is only available from the NeuroDebian repository. Please see http://neuro.debian.net for more information.

Please cite: David C. Van Essen, Heather A. Drury, James Dickson, John Harwell, Donna Hanlon and Charles H. Anderson: An Integrated Software Suite for Surface-based Analyses of Cerebral Cortex. (PubMed,eprint) Journal of American Medical Informatics Association 8(5):443-459 (2001)
Conquest-common
ConQuest DICOM Server - common files
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A full featured DICOM server that has been developed based on and heavily extending the public domain UCDMC DICOM code. Some possible applications of the ConQuest DICOM software are:

  • DICOM training and testing
  • Demonstration and research image archives
  • Image format conversion from a scanner with DICOM network access
  • DICOM image viewing and slide making
  • DICOM image selection, (limited) editing, and splitting and merging of series
  • Advanced scriptable image modification, filtering, forwarding and conversion
  • DICOM caching and archive merging

This package contains common files. You'll need a package providing conquest-dicom-server (e.g. conquest-mysql, conquest-postgres, conquest-sqlite or conquest-dbase).

Ctn
Central Test Node, a DICOM implementation for medical imaging
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DICOM is the standard for image storage, annotation, and networking. It is used widely for medical imaging. The Central Test Node software (CTN) provides an implementation of this standard.

This package includes the binary and run-time configuration files for CTN.

Please cite: S.M. Moore, S.A. Hoffman and D.E. Beecher: DICOM Shareware: A Public Implementation of the DICOM Standard 2165:772–781 (1994)
Ctsim
Computed tomography simulator
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CTSim provides an interactive computed tomography simulator. Computed tomography is the technique of estimating the interior of an object by measuring x-ray absorption through that object.

CTSim has both command-line tools and a graphical user interface. CTSim has very educational trace modes for viewing the data collection simulation as well as the reconstruction.

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Dcmtk
OFFIS DICOM toolkit command line utilities
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DCMTK includes a collection of libraries and applications for examining, constructing and converting DICOM image files, handling offline media, sending and receiving images over a network connection, as well as demonstrative image storage and worklist servers.

This package contains the DCMTK utility applications.

Note: This version was compiled with libssl support.

Dicom3tools
DICOM medical image files manipulation and conversion tools
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Command line utilities for creating, modifying, dumping and validating files of DICOM attributes. Support conversion of some proprietary medical image formats to DICOM. Can handle older ACR/NEMA format data, and some proprietary versions of that such as SPI.

Dicomnifti
converts DICOM files into the NIfTI format
Maintainer: NeuroDebian Team
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The dinifti program converts MRI images stored in DICOM format to NIfTI format. The NIfTI format is thought to be the new standard image format for medical imaging and can be used with for example with FSL, AFNI, SPM, Caret or Freesurfer.

dinifti converts single files, but also supports fully automatic batch conversions of complete dicomdirs. Additionally, converted NIfTI files can be properly named, using image series information from the DICOM files.

Dicomscope
OFFIS DICOM Viewer
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DICOMscope is a free DICOM viewer which can display uncompressed, monochrome DICOM images from all modalities and which supports monitor calibration according to DICOM part 14 as well as presentation states.

DICOMscope offers a print client (DICOM Basic Grayscale Print Management) which also implements the optional Presentation LUT SOP Class.

The development of this prototype was commissioned by the "Committee for the Advancement of DICOM" and demonstrated at the European Congress of Radiology ECR 1999. An enhanced version was developed for the "DICOM Display Consistency Demonstration" at RSNA InfoRAD 1999.

The current release has been demonstrated at ECR 2001 and contains numerous extensions, including a print server, support for encrypted DICOM communication, digital signatures and structured reporting.

Fslview
viewer for (f)MRI and DTI data
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This package provides a viewer for 3d and 4d MRI data as well as DTI images. FSLView is able to display ANALYZE and NIFTI files. The viewer supports multiple 2d viewing modes (orthogonal, lightbox or single slices), but also 3d volume rendering. Additionally FSLView is able to visualize timeseries and can overlay metrical and stereotaxic atlas data.

FSLView is part of FSL.

Please cite: S.M. Smith, M. Jenkinson, M.W. Woolrich, C.F. Beckmann, T.E.J. Behrens, H. Johansen-Berg, P.R. Bannister, M. De Luca, I. Drobnjak, D.E. Flitney, R. Niazy, J. Saunders, J. Vickers, Y. Zhang, N. De Stefano, J.M. Brady and P.M. Matthews: Advances in functional and structural MR image analysis and implementation as FSL. (PubMed) NeuroImage 23:208-219 (2004)
Remark of Debian Med team: fslview was removed from Debian (see #647810)

The bug log (http://bugs.debian.org/647810) explains the reasons for the removal. The maintainers did never respond whether they plan to bring back a more recent version of this package

Gdf-tools
IO library for the GDF -- helper tools
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GDF (General Dataformat for Biosignals) is intended to provide a generic storage for biosignals, such as EEG, ECG, MEG etc.

This package provides the tool shipped with the library (gdf_merger).

Ginkgocadx
Medical Imaging Software and complete DICOM Viewer
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Ginkgo CADx provides a complete DICOM viewer solution with advanced capabilities and support for extensions.

  • Easy and customizable interface through profiles.
  • Full featured DICOM image visualization.
  • Complete tool set (measure, markers, text, ...).
  • Multiple modalities support (Neurological, Radiological, Dermatological, Ophthalmological, Ultrasound, Endoscopy, ...)
  • Dicomization support from JPEG, PNG, GIF and TIFF.
  • Full EMH integration support: HL7 standard and IHE compliant workflows.
  • PACS Workstation (C-FIND, C-MOVE, C-STORE...)
  • Extensible through custom extensions.
  • Retinal image mosaic composition.
  • Automatic retinal analysis diagnostics.
  • Psoriasis automatic diagnostics.
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Gofigure2
Tool for visualizing, processing and analysing of bioimages
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Main objectives of GoFigure2 are to provide

  • interaction/visualization/navigation into 4D multichannels bio-images;
  • save/retrieve information related to the imaging process, analysis results;
  • extracting objects from bio-images (e.g. nucleii, cell-membranes...);
  • tracking sub-cellular structure, cells;
  • detecting and tracking cell-division through time;
  • generating and visualizing cell-lineage.
Gwyddion
Scanning Probe Microscopy visualization and analysis tool
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Gwyddion is a modular program for Scanning Probe Microscopy (SPM) data visualization and analysis. It is primarily intended for analysis of height field data obtained by microscopy techniques like

  • Atomic Force Microscopy (AFM),
  • Magnetic Force Microscopy (MFM),
  • Scanning Tunneling Microscopy (STM),
  • Near-field Scanning Optical Microscopy (SNOM or NSOM) and others. However, it can be used for arbitrary height field and image analysis.

This package contains the main application and its modules. It also contains a GNOME (and Xfce) thumbnailer which creates previews for all file types known to Gwyddion.

Gwyddion's Python scripting interface Pygwy is also included.

Please cite: David Nečas and Petr Klapetek: Gwyddion: an open-source software for SPM data analysis. (eprint) Central European Journal of Physics 10(1):181-188 (2012)
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Imagej
Image processing program inspired by NIH Image
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It can display, edit, analyze, process, save and print 8-bit, 16-bit and 32-bit images. It can read many image formats including TIFF, GIF, JPEG, BMP, DICOM, FITS and "raw". It supports "stacks", a series of images that share a single window.

It can calculate area and pixel value statistics of user-defined selections. It can measure distances and angles. It can create density histograms and line profile plots. It supports standard image processing functions such as contrast manipulation, sharpening, smoothing, edge detection and median filtering.

Spatial calibration is available to provide real world dimensional measurements in units such as millimeters. Density or gray scale calibration is also available.

ImageJ is developed by Wayne Rasband (wayne@codon.nih.gov), is at the Research Services Branch, National Institute of Mental Health, Bethesda, Maryland, USA.

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Imagevis3d
desktop volume rendering application for large data
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ImageVis3D is a volume rendering application specifically designed to render large data. This is achieved by splitting the dataset into multiple levels of detail (LoD), with each level itself decomposed into multiple bricks (atomic rendering primitive). Interaction occurs at the coarsest LoD, which can be rendered instantaneously on almost all modern systems. After a configurable delay, ImageVis3D will successively render finer levels of detail, until the data are visible at their native resolution.

Development of ImageVis3D is sponsored by the NIH/NCRR Center for Integrative Biomedical Computing (CIBC), and the DOE Visualization And Analytics Center for Enabling Technologies (VACET).

Invesalius
3D medical imaging reconstruction software
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InVesalius generates 3D medical imaging reconstructions based on a sequence of 2D DICOM files acquired with CT or MRI equipments. InVesalius is internationalized (currently available in English, Portuguese, French, German, Spanish, Greek and Chinese) and provides several tools:

  • DICOM support including: (a) ACR-NEMA version 1 and 2; (b) DICOM version 3.0 (including various encodings of JPEG -lossless and lossy-, RLE)
  • Image manipulation features (zoom, pan, rotation, brightness/contrast, etc)
  • Segmentation based on 2D slices
  • Pre-defined threshold ranges according to tissue of interest
  • Edition tools (similar to Paint Brush) based on 2D slices
  • 3D surface creation
  • 3D surface connectivity tools
  • 3D surface exportation (including: binary STL, OBJ, VRML, Inventor)
  • High-quality volume rendering projection
  • Pre-defined volume rendering presets
  • Volume rendering crop plane
  • Picture exportation (including: BMP, TIFF, JPG, PostScript, POV-Ray)
  • Minimum, Maximum or Mean Intensity Projection, Maximum Intensity Difference Accumulation and Contour based visualizations
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Itksnap
semi-automatic segmentation of structures in 3D images
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SNAP provides semi-automatic segmentation of structures in medical images (e.g. magnetic resonance images of the brain) using active contour methods, as well as manual delineation and image navigation. Noteworthy features are:

  • Linked cursor for seamless 3D navigation
  • Manual segmentation in three orthogonal planes at once
  • Support for many different 3D image formats, including NIfTI
  • Support for concurrent, linked viewing and segmentation of multiple images
  • Limited support for color images (e.g., diffusion tensor maps)
  • 3D cut-plane tool for fast post-processing of segmentation results
Please cite: Paul A. Yushkevich, Joseph Piven, Heather Cody Hazlett, Rachel Gimpel Smith, Sean Ho, James C. Gee and Guido Gerig: User-guided 3D active contour segmentation of anatomical structures: Significantly improved efficiency and reliability. Neuroimage 31:1116-1128 (2006)
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King
interactive system for three-dimensional vector graphics
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KiNG (Kinemage, Next Generation) is an interactive system for three-dimensional vector graphics. It supports a set of graphics primitives that make it suitable for many types of graphs, plots, and other illustrations; although its first use was to display macromolecular structures for biophysical research. KiNG builds on Mage, JavaMage, and the "kinemage" (kinetic image) concept to deliver a full-featured Java application with a user-friendly interface and integrated editing features. The KiNG jar file can be used within a web page as a Java applet or Java object to promote easy access to kinemages or coordinate files from a web browser.

Libgdcm-tools
Grassroots DICOM tools and utilities
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Grassroots DiCoM is a C++ library for DICOM medical files. It is automatically wrapped to python/C#/Java (using swig). It supports RAW,JPEG (lossy/lossless),J2K,JPEG-LS, RLE and deflated.

Install this package for the gdcmanon, gdcmconv, gdcmdiff, gdcmdump, gdcmpap3, gdcmgendir, gdcmimg, gdcminfo, gdcmpdf, gdcmraw, gdcmscanner, gdcmscu, gdcmtar, gdcmxml programs.

Please cite: David Rodríguez González, Trevor Carpenter, Jano I. van Hemert and Joanna Wardlaw: An open source toolkit for medical imaging de-identification. (PubMed,eprint) European Radiology 20(8):1896-1904 (2010)
Lipsia
analysis suite for MRI and fMRI data
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Leipzig Image Processing and Statistical Inference Algorithms (LIPSIA)

This is a software package for the data processing and evaluation of functional magnetic resonance images. The analysis of fMRI data comprises various aspects including filtering, spatial transformation, statistical evaluation as well as segmentation and visualization. All these aspects are covered by LIPSIA. For the statistical evaluation, a number of well established and peer-reviewed algorithms were implemented in LIPSIA that allow an efficient and user-friendly processing of fMRI data sets. As the amount of data that must be handled is enormous, an important aspect in the development of LIPSIA was the efficiency of the software implementation.

LIPSIA operates exclusively on data in the VISTA data format. However, the package contains converters for medical image data in iBruker, ANALYZE and NIfTI format -- converting VISTA images into NIfTI files is also supported.

Remark of Debian Med team: lipsia was removed from Debian (see #674295)

The bug log (http://bugs.debian.org/674295) explains the reasons for the removal and the conditions when a new version might be back

Medcon
Medical Image (DICOM, ECAT, ...) conversion tool
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This project stands for Medical Image Conversion. Released under the (L)GPL, it comes with the full C-source code of the library, a flexible command line utility and a neat graphical front-end using the GTK+ toolkit. The currently supported formats are: Acr/Nema 2.0, Analyze (SPM), DICOM 3.0, InterFile 3.3 and PNG.

The program also allows one to read unsupported files without compression, to print pixel values or to extract/reorder specified images. It is possible to retrieve the raw binary/ascii image arrays or to write PNG for desktop applications.

This is the command line tool for batch processing.

Mia-tools
Command line tools for gray scale image processing
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Command lines tools to run general purpose image processing tasks on 2D and 3D gray scale images, and basic operations on triangular meshes. Supported image processing algorithms are image filtering, combining, image registration, motion compensation for image series, and the estimation of various statistics over images.

The package is enhanced by the following packages: mia-tools-doc
Please cite: Gert Wollny, Jean-Jaques Hublin, Maria-J Ledesma-Carbayo, Matthew M. Skinner, Peter Kellman and Thomas Hierl: MIA - A Free and Open Source Software for Gray Scale Medical Image Analysis. (eprint) Source Code for Biology and Medicine 8:20 (2013)
Mia-viewit
Viewer program for 3D data sets created by using MIA
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MIA viewer program for the visualization of 3D data sets. The interfaces and supported data types focus on the results that can be obtained by running programs from the mia-tools package.

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Mialmpick
Tools for landmark picking in 3D volume data sets
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This tool provides a simple 3D renderer that can visualize surfaces directly from 3D volumes and can be used to set 3D landmarks. It is best suited for CT data sets.

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Minc-tools
MNI medical image format tools
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This package contains tools to manipulate MINC files.

The Minc file format is a highly flexible medical image file format built on top of the NetCDF generalized data format. The format is simple, self-describing, extensible, portable and N-dimensional, with programming interfaces for both low-level data access and high-level volume manipulation. On top of the libraries is a suite of generic image-file manipulation tools. The format, libraries and tools are designed for use in a medical-imaging research environment: they are simple and powerful and make no attempt to provide a pretty interface to users.

Mriconvert
medical image file conversion utility
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MRIConvert is a medical image file conversion utility that converts DICOM files to NIfTI 1.1, Analyze 7.5, SPM99/Analyze, BrainVoyager, and MetaImage volume formats.

Mricron
magnetic resonance image conversion, viewing and analysis
Maintainer: NeuroDebian Team
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This is a GUI-based visualization and analysis tool for (functional) magnetic resonance imaging. MRIcron can be used to create 2D or 3D renderings of statistical overlay maps on brain anatomy images. Moreover, it aids drawing anatomical regions-of-interest (ROI), or lesion mapping, as well as basic analysis of functional timeseries (e.g. creating plots of peristimulus signal-change).

In addition to 'mricron', this package also provides 'dcm2nii' that supports converting DICOM and PAR/REC images into the NIfTI format, and 'npm' for non-parametric data analysis.

Please cite: Chris Rorden, Hans-Otto Karnath, Leonardo Bonilha: Improving lesion-symptom mapping. (2007)
Mrtrix
diffusion-weighted MRI white matter tractography
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Set of tools to perform diffusion-weighted MRI white matter tractography of the brain in the presence of crossing fibres, using Constrained Spherical Deconvolution, and a probabilisitic streamlines algorithm. Magnetic resonance images in DICOM, ANALYZE, or uncompressed NIfTI format are supported.

Nifti-bin
tools shipped with the NIfTI library
Maintainer: NeuroDebian Team
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Niftilib is a set of i/o libraries for reading and writing files in the NIfTI-1 data format. NIfTI-1 is a binary file format for storing medical image data, e.g. magnetic resonance image (MRI) and functional MRI (fMRI) brain images.

This package provides the tools that are shipped with the library (nifti_tool, nifti_stats and nifti1_test).

Odin
develop, simulate and run magnetic resonance sequences
Maintainer: NeuroDebian Team
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ODIN is a framework for magnetic resonance imaging (MRI). It covers the whole toolchain of MRI, from low-level data acquisition to image reconstruction. In particular, it aims at rapid prototyping of MRI sequences. The sequences can be programmed using a high-level, object oriented, C++ programming interface. It provides advanced sequence analysis tools, such as interactive plotting of k-space trajectories, a user interface for a fast compile-link-test cycle and a powerful MRI simulator which supports different virtual samples. For fast and flexible image reconstruction, ODIN contains a highly customizable, multi-threaded data-processing framework.

Please cite: Thies H. Jochimsen, Michael von Mengershausen: ODIN: Object-oriented development interface for NMR. (2004)
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Openmeeg-tools
openmeeg library -- command line tools
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OpenMEEG consists of state-of-the art solvers for forward problems in the field of MEG and EEG. Solvers are based on the symmetric Boundary Element method [Kybic et al, 2005], providing excellent accuracy, particularly for superficial cortical sources. OpenMEEG can compute four types of lead fields (EEG, MEG, Internal Potential and Electrical Impedence Tomography).

This package provides command line interface to openmeeg functionality.

Please cite: Alexandre Gramfort, Théodore Papadopoulo, Emmanuel Olivi and Maureen Clerc: OpenMEEG: opensource software for quasistatic bioelectromagnetics. (PubMed,eprint) BioMedical Engineering OnLine 9:45 (2010)
Openslide-tools
Manipulation and conversion tools for OpenSlide
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OpenSlide is a C library that provides a simple interface to read whole-slide images also known as virtual slides.

Whole-slide images, also known as virtual slides, are large, high resolution images used in digital pathology. Reading these images using standard image tools or libraries is a challenge because these tools are typically designed for images that can comfortably be uncompressed into RAM or a swap file. Whole-slide images routinely exceed RAM sizes, often occupying tens of gigabytes when uncompressed. Additionally, whole-slide images are typically multi-resolution, and only a small amount of image data might be needed at a particular resolution.

This library currently supports:

  • Aperio (.svs, .tif)
  • Hamamatsu (.vms, .vmu, .ndpi)
  • Leica (.scn)
  • MIRAX (.mrxs)
  • Sakura (.svslide)
  • Trestle (.tif)
  • Generic tiled TIFF (.tif)

This package contains command line tools for file manipulation.

Orthanc
RESTful DICOM server for healthcare and medical research
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Orthanc aims at providing a simple, yet powerful standalone DICOM server. Orthanc can turn any computer running Windows or Linux into a DICOM store (in other words, a mini-PACS system). Its architecture is lightweight, meaning that no complex database administration is required, nor the installation of third-party dependencies.

What makes Orthanc unique is the fact that it provides a RESTful API. Thanks to this major feature, it is possible to drive Orthanc from any computer language. The DICOM tags of the stored medical images can be downloaded in the JSON file format. Furthermore, standard PNG images can be generated on-the-fly from the DICOM instances by Orthanc.

Orthanc lets its users focus on the content of the DICOM files, hiding the complexity of the DICOM format and of the DICOM protocol.

Please cite: S. Jodogne, C. Bernard, M. Devillers, E. Lenaerts and P. Coucke: Orthanc -- A Lightweight, RESTful DICOM Server for Healthcare and Medical Research (2013)
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Pixelmed-apps
DICOM implementation containing Image Viewer and a ECG Viewer - jnlp
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This is a stand-alone DICOM toolkit that implements code for reading and creating DICOM data, DICOM network and file support, a database of DICOM objects, support for display of directories, images, reports and spectra, and DICOM object validation.

Provide command line applications for using pixelmed

Plastimatch
medical image reconstruction and registration
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Plastimatch is an open source software for deformable image registration. It is designed for high-performance volumetric registration of medical images, such as X-ray computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET). Software features include:

  • B-spline method for deformable image registration (GPU and multicore accelerated), including support for image masking, landmark penalties, and regularization
  • Demons method for deformable image registration (GPU accelerated)
  • Multi-atlas segmentation
  • ITK-based algorithms for translation, rigid, affine, multiple demons methods, and B-spline registration
  • Pipelined, multi-stage registration framework with seamless conversion between most algorithms and transform types
  • Landmark-based deformable registration using thin- plate splines for global registration
  • Landmark-based deformable registration using radial basis functions for local corrections
  • Broad support for 3D image file formats (using ITK), including DICOM, Nifti, NRRD, MetaImage, and Analyze
  • Extensive toolchain for radiotherapy research, including support for DICOM, DICOM-RT, DICOM SRO, XiO file format, gamma analysis, contour manipulation, contour overlap analysis, and vector field analysis Plastimatch also features two handy utilities which are not directly related to image registration:

  • FDK cone-beam CT reconstruction (GPU and multicore accelerated)

  • Digitally reconstructed radiograph (DRR) generation (GPU and multicore accelerated)
Python-dicom
DICOM medical file reading and writing
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pydicom is a pure Python module for parsing DICOM files. DICOM is a standard (http://medical.nema.org) for communicating medical images and related information such as reports and radiotherapy objects.

pydicom makes it easy to read DICOM files into natural pythonic structures for easy manipulation. Modified datasets can be written again to DICOM format files.

Python-dipy
toolbox for analysis of MR diffusion imaging data
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Dipy is a toolbox for the analysis of diffusion magnetic resonance imaging data. It features:

  • Reconstruction algorithms, e.g. GQI, DTI
  • Tractography generation algorithms, e.g. EuDX
  • Intelligent downsampling of tracks
  • Ultra fast tractography clustering
  • Resampling datasets with anisotropic voxels to isotropic
  • Visualizing multiple brains simultaneously
  • Finding track correspondence between different brains
  • Warping tractographies into another space, e.g. MNI space
  • Reading many different file formats, e.g. Trackvis or NIfTI
  • Dealing with huge tractographies without memory restrictions
  • Playing with datasets interactively without storing
Python-mvpa2
multivariate pattern analysis with Python v. 2
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PyMVPA eases pattern classification analyses of large datasets, with an accent on neuroimaging. It provides high-level abstraction of typical processing steps (e.g. data preparation, classification, feature selection, generalization testing), a number of implementations of some popular algorithms (e.g. kNN, Ridge Regressions, Sparse Multinomial Logistic Regression), and bindings to external machine learning libraries (libsvm, shogun).

While it is not limited to neuroimaging data (e.g. fMRI, or EEG) it is eminently suited for such datasets.

This is a package of PyMVPA v.2. Previously released stable version is provided by the python-mvpa package.

The package is enhanced by the following packages: python-sklearn
Python-nibabel
Python bindings to various neuroimaging data formats
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NiBabel provides read and write access to some common medical and neuroimaging file formats, including: ANALYZE (plain, SPM99, SPM2), GIFTI, NIfTI1, MINC, as well as PAR/REC. The various image format classes give full or selective access to header (meta) information and access to the image data is made available via NumPy arrays. NiBabel is the successor of PyNIfTI.

This package also provides a commandline tools:

  • dicomfs - FUSE filesystem on top of a directory with DICOMs
  • nib-ls - 'ls' for neuroimaging files
  • parrec2nii - for conversion of PAR/REC to NIfTI images
Python-nipy
Analysis of structural and functional neuroimaging data
Maintainer: NeuroDebian Team
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NiPy is a Python-based framework for the analysis of structural and functional neuroimaging data. It provides functionality for

  • General linear model (GLM) statistical analysis
  • Combined slice time correction and motion correction
  • General image registration routines with flexible cost functions, optimizers and re-sampling schemes
  • Image segmentation
  • Basic visualization of results in 2D and 3D
  • Basic time series diagnostics
  • Clustering and activation pattern analysis across subjects
  • Reproducibility analysis for group studies
Python-nipype
Neuroimaging data analysis pipelines in Python
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Nipype interfaces Python to other neuroimaging packages and creates an API for specifying a full analysis pipeline in Python. Currently, it has interfaces for SPM, FSL, AFNI, Freesurfer, but could be extended for other packages (such as lipsia).

Please cite: SS Ghosh, C Burns, D Clark, K Gorgolewski, YO Halchenko, C Madison, R Tungaraza and KJ Millman: Nipype: Opensource platform for unified and replicable interaction with existing neuroimaging tools (eprint) 16th Annual Meeting of the Organization for Human Brain Mapping :106 (2010)
Python-nitime
timeseries analysis for neuroscience data (nitime)
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Nitime is a Python module for time-series analysis of data from neuroscience experiments. It contains a core of numerical algorithms for time-series analysis both in the time and spectral domains, a set of container objects to represent time-series, and auxiliary objects that expose a high level interface to the numerical machinery and make common analysis tasks easy to express with compact and semantically clear code.

Python-surfer
visualize Freesurfer's data in Python
Maintainer: NeuroDebian Team
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This is a Python package for visualization and interaction with cortical surface representations of neuroimaging data from Freesurfer. It extends Mayavi’s powerful visualization engine with a high-level interface for working with MRI and MEG data.

PySurfer offers both a command-line interface designed to broadly replicate Freesurfer’s Tksurfer program as well as a Python library for writing scripts to efficiently explore complex datasets.

Sigviewer
GUI viewer for biosignals such as EEG, EMG, and ECG
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SigViewer is a viewing and scoring software for biomedical signal data. It relies on biosig4c++ library which supports a number of data formats (including EDF, BDF, GDF, BrainVision, BCI2000, CFWB, HL7aECG, SCP_ECG (EN1064), MFER, ACQ, CNT(Neuroscan), DEMG, EGI, EEG1100, FAMOS, SigmaPLpro, TMS32). The complete list of supported file formats is available at http://pub.ist.ac.at/~schloegl/biosig/TESTED .

Besides displaying biosignals, SigViewer supports creating annotations to select artifacts or specific events.

Slicer
software package for visualization and image analysis - main application
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Slicer is an application for computer scientists and clinical researchers. The platform provides functionality for segmentation, registration and three-dimensional visualization of multi-modal image data, as well as advanced image analysis algorithms for diffusion tensor imaging, functional magnetic resonance imaging and image-guided therapy. Standard image file formats are supported, and the application integrates interface capabilities to biomedical research software and image informatics frameworks.

3D Slicer main application.

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The bug log (http://bugs.debian.org/644352) explains the reasons for the removal and the conditions when a new version might be back

Sofa-apps
GUI for the Simulation Open Framework Architecture (SOFA)
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SOFA is an Open Source framework primarily targeted at real-time simulation, with an emphasis on medical simulation. It is mostly intended for the research community to help develop newer algorithms, but can also be used as an efficient prototyping tool.

This package contains the SOFA main application.

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Teem-apps
Tools to process and visualize scientific data and images - command line tools
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Teem is a coordinated group of libraries for representing, processing, and visualizing scientific raster data. Teem includes command-line tools that permit the library functions to be quickly applied to files and streams, without having to write any code. The most important and useful libraries in Teem are:

  • Nrrd (and the unu command-line tool on top of it) supports a range of operations for transforming N-dimensional raster data (resample, crop, slice, project, histogram, etc.), as well as the NRRD file format for storing arrays and their meta-information.
  • Gage: fast convolution-based measurements at arbitrary point locations in volume datasets (scalar, vector, tensor, etc.)
  • Mite: a multi-threaded ray-casting volume render with transfer functions based on any quantity Gage can measure
  • Ten: for estimating, processing, and visualizing diffusion tensor fields, including fiber tractography methods.

This package contains some simple command-line tools which provide fast and easy access to the functionality in the various libraries.

Tifffile
read image and metadata from TIFF, STK, LSM, OME-TIFF and FluoView files
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Only a subset of the TIFF specification is supported, mainly uncompressed and losslessly compressed 1-32 bit integer as well as 32 and 64-bit float images, which are commonly used in scientific imaging.

This tool is implemented to support TIFF with custom extensions, namely:

  • STK (MetaMorph)
  • LSM (Carl Zeiss MicroImaging)

Currently only primary info records are read for STK, FluoView, and NIH image formats.

Voxbo
processing, statistical analysis, and display of brain imaging data
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This is a toolkit for analysis of functional neuroimaging (chiefly fMRI) experiments and voxel-based lesion-behavior mapping. VoxBo supports the modified GLM (for autocorrelated data), as well as the standard GLM for non-autocorrelated data. The toolkit is designed to be interoperable with AFNI, FSL, SPM and others.

Please register by following this link if you are using voxbo.
Vtk-dicom-tools
DICOM for VTK - tools
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This package contains a set of classes for managing DICOM files and metadata from within VTK, and some utility programs for interrogating and converting DICOM files.

Command line tools

Xmedcon
Medical Image (DICOM, ECAT, ...) conversion tool (GUI)
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This project stands for Medical Image Conversion. Released under the (L)GPL, it comes with the full C-source code of the library, a flexible command line utility and a neat graphical front-end using the GTK+ toolkit. The currently supported formats are: Acr/Nema 2.0, Analyze (SPM), DICOM 3.0, InterFile 3.3 and PNG.

The program also allows one to read unsupported files without compression, to print pixel values or to extract/reorder specified images. It is possible to retrieve the raw binary/ascii image arrays or to write PNG for desktop applications.

This is the program version for X based on GTK+. Processes only one file at a time.

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Cmtk
Computational Morphometry Toolkit
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A software toolkit for computational morphometry of biomedical images, CMTK comprises a set of command line tools and a back-end general-purpose library for processing and I/O.

The command line tools primarily provide the following functionality: registration (affine and nonrigid; single and multi-channel; pairwise and groupwise), image correction (MR bias field estimation; interleaved image artifact correction), processing (filters; combination of segmentations via voting and STAPLE; shape-based averaging), statistics (t-tests; general linear regression).

Please cite: T. Rohlfing: User Guide to The Computational Morphometry Toolkit. (eprint) The Insight Journal (2009)
Connectomeviewer
Interactive Analysis and Visualization for MR Connectomics
Maintainer: Stephan Gerhard
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The Connectome Viewer is a extensible, scriptable, pythonic research environment for visualization and (network) analysis in neuroimaging and connectomics.

Employing the Connectome File Format, diverse data types such as networks, surfaces, volumes, tracks and metadata are handled and integrated. The Connectome Viewer is part of the MR Connectome Toolkit.

Please cite: Gerhard S, Daducci A, Lemkaddem A, Meuli R, Thiran J-P and Hagmann P: The Connectome Viewer Toolkit: An open source framework to manage, analyze, and visualize connectomes. (2011)
Conquest-dbase
ConQuest DICOM Server - DBaseIII backend
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A full featured DICOM server that has been developed based on and heavily extending the public domain UCDMC DICOM code. Some possible applications of the ConQuest DICOM software are:

  • DICOM training and testing
  • Demonstration and research image archives
  • Image format conversion from a scanner with DICOM network access
  • DICOM image viewing and slide making
  • DICOM image selection, (limited) editing, and splitting and merging of series
  • Advanced scriptable image modification, filtering, forwarding and conversion
  • DICOM caching and archive merging

This package uses DBaseIII files as database backend.

Conquest-mysql
ConQuest DICOM Server - MySQL backend
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A full featured DICOM server that has been developed based on and heavily extending the public domain UCDMC DICOM code. Some possible applications of the ConQuest DICOM software are:

  • DICOM training and testing
  • Demonstration and research image archives
  • Image format conversion from a scanner with DICOM network access
  • DICOM image viewing and slide making
  • DICOM image selection, (limited) editing, and splitting and merging of series
  • Advanced scriptable image modification, filtering, forwarding and conversion
  • DICOM caching and archive merging

This package uses MySQL as database backend.

Conquest-postgres
ConQuest DICOM Server - PostgreSQL backend
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A full featured DICOM server that has been developed based on and heavily extending the public domain UCDMC DICOM code. Some possible applications of the ConQuest DICOM software are:

  • DICOM training and testing
  • Demonstration and research image archives
  • Image format conversion from a scanner with DICOM network access
  • DICOM image viewing and slide making
  • DICOM image selection, (limited) editing, and splitting and merging of series
  • Advanced scriptable image modification, filtering, forwarding and conversion
  • DICOM caching and archive merging

This package uses PostgreSQL as database backend.

Conquest-sqlite
ConQuest DICOM Server - SQLite backend
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A full featured DICOM server that has been developed based on and heavily extending the public domain UCDMC DICOM code. Some possible applications of the ConQuest DICOM software are:

  • DICOM training and testing
  • Demonstration and research image archives
  • Image format conversion from a scanner with DICOM network access
  • DICOM image viewing and slide making
  • DICOM image selection, (limited) editing, and splitting and merging of series
  • Advanced scriptable image modification, filtering, forwarding and conversion
  • DICOM caching and archive merging

This package uses SQLite as database backend.

Elastix
toolbox for rigid and nonrigid registration of images
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Image registration based on the well-known Insight Segmentation and Registration Toolkit (ITK). The software consists of a collection of algorithms that are commonly used to solve (medical) image registration problems. The modular design of elastix allows the user to quickly configure, test, and compare different registration methods for a specific application. A command-line interface enables automated processing of large numbers of data sets, by means of scripting.

Please register by following this link if you are using elastix.
Please cite: Stefan Klein, Marius Staring, Keelin Murphy and Max A. Viergever, Josien P. W. Pluim: elastix: A Toolbox for Intensity-Based Medical Image Registration. (PubMed) IEEE Transactions on Medical Imaging 29(1):196 - 205 (2010)
Imagemagick
image manipulation programs -- binaries
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ImageMagick is a software suite to create, edit, and compose bitmap images. It can read, convert and write images in a variety of formats (over 100) including DPX, EXR, GIF, JPEG, JPEG-2000, PDF, PhotoCD, PNG, Postscript, SVG, and TIFF. Use ImageMagick to translate, flip, mirror, rotate, scale, shear and transform images, adjust image colors, apply various special effects, or draw text, lines, polygons, ellipses and Bézier curves. All manipulations can be achieved through shell commands as well as through an X11 graphical interface (display).

This package include links to quantum depth specific binaries and manual pages.

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Imview
Image viewing and analysis application
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Imview is an application which

  • Displays a large number of image formats.
  • Displays 2D or 3D (as slices) images with a very good zoom and pan feature.
  • Works with multi-spectral, time series or multi-page documents (e.g.: Satellite images, TIFF stacks, animated GIFs and heterogeneous multi-component files).
  • Displays all pixel types (1-bit to 64-bit data, integer or floating point).
  • Arbitrary 1-D profile of 2-D images (or of 2-D slices of 3-D images) can be displayed.
  • Has support for arbitrary colourmaps for all pixel types (i.e.: false colour display).
  • Has standard image manipulation facilities (brightness/contrast, gamma, zoom, crop, rotation, etc).
  • Can be controlled remotely via sockets and text commands (for easy integration into various image analysis systems).
  • Images can be uploaded into Imview via sockets or shared memory.
  • And much more!
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Openwalnut-qt4
Qt based user interface for OpenWalnut
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OpenWalnut is a tool for multi-modal medical and brain data visualization. Its universality allows it to be easily extended and used in a large variety of application cases. It is both, a tool for the scientific user and a powerful framework for the visualization researcher. Besides others, it is able to load NIfTI data, VTK line data and RIFF-format CNT/AVR-files. OpenWalnut provides many standard visualization tools like line integral convolution (LIC), isosurface-extraction, glyph-rendering or interactive fiber-data exploration. The powerful framework of OpenWalnut allows researchers and power-users to easily extend the functionality to their specific needs.

This package contains the QT4 GUI for OpenWalnut.

Please cite: Sebastian Eichelbaum, Mario Hlawitschka, Alexander Wiebel, Gerik Scheuermann: OpenWalnut - An Open-Source Visualization System (2010)
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Paraview
Parallel Visualization Application
Maintainer: Debian Science Team
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ParaView is an open-source, multi-platform application designed to visualize data sets of size varying from small to very large. The goals of the ParaView project include the following:

* Develop an open-source, multi-platform visualization application.
* Support distributed computation models to process large data sets.
* Create an open, flexible, and intuitive user interface.
* Develop an extensible architecture based on open standards.

ParaView runs on distributed and shared memory parallel as well as single processor systems and has been successfully tested on Windows, Mac OS X, Linux and various Unix workstations, clusters and supercomputers. Under the hood, ParaView uses the Visualization Toolkit as the data processing and rendering engine and has a user interface written using Qt.

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Pngquant
PNG (Portable Network Graphics) image optimising utility
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pngquant is a command-line conversion utility to quantize and dither truecolor PNG images, especially those with a full alpha channel, down to 8-bit (or smaller) RGBA-palette PNGs. Such images are usually two to four times smaller than the full 32-bit versions, and partial transparency is preserved quite nicely. This makes pngquant especially useful both for Web sites and for PlayStation 2 development, where one of the texture formats is RGBA-palette-based (though not PNG-compressed). This is the same technique used for many of the images on the Miscellaneous Transparent PNGs page (http://www.libpng.org/pub/png/pngs-img.html), and the results are often indistinguishable from the original, truecolor PNG images.

Optimizers (like pngcrush and optipng) optimize the compression, usually losslessly, while pngquant quantizes colors down to 256 (or fewer) distinct RGBA combinations, which is lossy.

Python-pyxid
interface for Cedrus XID and StimTracker devices
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pyxid is a Python library for interfacing with Cedrus XID (eXperiment Interface Device) and StimTracker devices. XID devices are used in software such as SuperLab, Presentation, and ePrime for receiving input as part of stimulus/response testing experiments.

pyxid handles all of the low level device handling for XID devices in Python projects.

Trimage
GUI and command-line interface to optimize image files
Maintainer: Kilian Valkhof
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Trimage is a cross-platform GUI and command-line interface to optimize image files via optipng, advpng, pngcrush and jpegoptim, depending on the filetype (currently, PNG and JPG files are supported). All image files are losslessly compressed on the highest available compression levels. Trimage gives you various input functions to fit your own workflow: A regular file dialog, dragging and dropping and various command line options.

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Fsl
transitional dummy package
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The only purpose of this package is to enable upgrades to the new 'fsl-core' package which replaces 'fsl'. This package can safely be removed.

Users aiming to perform a complete FSL installation (including all data components) are advised to install the 'fsl-complete' package from NeuroDebian.

Please register by following this link if you are using fsl.
Please cite: Mark Jenkinson, Christian F. Beckmann, Timothy E. J. Behrens, Mark W. Woolrich and Stephen M. Smith: FSL. (PubMed) NeuroImage 62(2):782-790 (2012)
Vmtk
the Vascular Modeling Toolkit
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The Vascular Modeling Toolkit is a collection of libraries and tools for 3D reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modeling of blood vessels.

Packaging has started and developers might try the packaging code in VCS

Afni
toolkit for analyzing and visualizing functional MRI data
License: GPL-2+
Git
Version: 0.20140910~dfsg.1-1

AFNI is an environment for processing and displaying functional MRI data. It provides a complete analysis toolchain, including 3D cortical surface models, and mapping of volumetric data (SUMA).

In addition to its own format, AFNI understands the NIfTI format and is therefore integrates easily with FSL and FreeSurfer.

Bioimagesuite
integrated image analysis software suite
License: GPL-2+
Debian package not available
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Version: 2.0-1

BioImage Suite has extensive capabilities for both neuro/cardiac and abdominal image analysis and state of the art visualization. Many packages are available that are highly extensible, and provide functionality for image visualization and registration, surface editing, cardiac 4D multi-slice editing, diffusion tensor image processing, mouse segmentation and registration, and much more. It can be integrated with other biomedical image processing software, such as FSL and SPM. This site provides information, downloads, documentation, and other resources for users of the software.

BioImage Suite was developed at Yale University and has been extensively used at different labs at Yale since 2004.

Remark of Debian Med team: Contact to upstream

There is a forum at BioImage Suite site for discussion of compiling it from source and packaging issues at http://research.yale.edu/bioimagesuite/forum/index.php?board=12.0

Bioimagexd
Analyzing, processing and visualizing of multi dimensional microscopy images
License: GPLv2
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Version: 1.0-1

BioImageXD is a multi-purpose post-processing tool for bioimaging. The software can be used for simple visualization of multi-channel temporal image stacks to complex 3D rendering of multiple channels at once. Animations of 3D renderings can be created using flying paths or keyframes. BioImageXD has basic image adjustment operations and a collection of noise reduction methods. Processing methods are accompanied with a selection of segmentation methods. Segmentation results can be analysed for tens of parameters or used for motion tracking. Other quantitative analysis methods include for instance voxel and object colocalization methods and internalization analysis. All processing and analysis methods can be build into pipelines and run for hundreds of datasets at once in batch processor.

Cellprofiler
quantitatively measure phenotypes from images automatically
License: GPL-2
Debian package not available
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Version: 2.0~svn11717-1

CellProfiler is cell image analysis software designed to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically.

Crea
base library of the creaTools medical image processing suite
License: CeCILL-B
Debian package not available
Git
Version: 0.0.20131107-1

The CreaTools are a suite of medical image processing and visualization software and development tools. They are developed by CREATIS, a research unit with extensive experience in the medical image processing field.

The CreaTools are a set of tools designed to meet both the needs of the end-users (physicians, students or researchers) and of the developers.

Dicoogle
Java Advanced Imaging API reference implementation
License: free
Debian package not available
Svn
Version: 0.4-1

This project contains the source code for the core Java Advanced Imaging API reference implementation containing the packages javax.media.jai. and com.sun.media.jai..

Incf-nidash-oneclick-clients
utility for pushing DICOM data to the INCF datasharing server
Responsible: NeuroDebian Team
License: BSD
Debian package not available
Vcs
Language: Python

A command line utility for anonymizing and sending DICOM data to the XNAT image database at the International Neuroinformatics Coordinating Facility (INCF). This tool is maintained by the INCF NeuroImaging DataSharing (NIDASH) task force.

Insightapplications - wnpp
InsightToolKit (ITK) based medical imaging applications
License: BSD
Debian package not available
Svn
Version: 3.20.0-1

A variety of applications providing segmentation, registration, and other medical image processing algorithms such as MRI bias field correction.

Jist - wnpp
Java Image Science Toolkit
License: free
Debian package not available
Git
Version: 2.0.20100907.dfsg1-1

Java Image Science Toolkit (JIST) provides a native Java-based imaging processing environment similar to the ITK/VTK paradigm. Initially developed as an extension to MIPAV (CIT, NIH, Bethesda, MD), the JIST processing infrastructure provides automated GUI generation for application plug-ins, graphical layout tools, and command line interfaces.

Kradview
medical image viewer for DICOM images
License: GPL-3+
Debian package not available
Svn
Version: 1.1.0-1

Kradview is a viewer of images obtained for some different sources: X-ray, NMR and DICOM-compatible imaging devices. Its aim is a easy to use DICOM viewer with instant rendering of images, no matter the size and the zoom of the DICOM image. It covers the "let's see the the X-ray image" need of the medical professional.

Libdcm4che-java
Clinical Image and Object Management
License: Apache-2.0 or LGPL-2
Debian package not available
Svn
Version: 2.0.25-1

Dcm4che is a collection of open source applications and utilities for the healthcare enterprise. At the core of the dcm4che project is a robust implementation of the DICOM standard. The dcm4che-1.x DICOM toolkit is used in many production applications across the world, while the current (2.x) version of the toolkit has been re-architected for high performance and flexibility.

Remark of Debian Med team: Needs jai_imageio as prerequsite

Building the package using the packaging code in SVN works up to a point were jai_imageio.jar is required. For the status of packaging this prerequisite see the Debian Java mailing list at http://lists.debian.org/debian-java/2011/04/msg00045.html

Mayam
Cross-platform DICOM Viewer
License: MPL 1.1/GPL 2.0/LGPL 2.1
Debian package not available
Svn
Version: 0.8-1

A Cross-platform DICOM viewer using the dcm4che toolkit.

The current features are:

  • DICOM Listener for Q/R
  • DICOM Send
  • Local DB for storing study information
  • Importing DICOM studies from local disk
  • Parsing DicomDir from local disk or CD
  • Query compressed studies without decompressing them
  • Multiple Studies viewer using Layout,Tab view
  • Export to JPEG (Study, Series, Instance level). Windowing can be applied to a single instance or series of instance while exporting
  • Cine Loop & stack navigation
  • Toggle for Text and Annotation Overlay
  • Windowing Presets Settings (based on modality)
  • Layout Settings (based on modality)
  • AE Management
  • DICOM Tags Viewer
Micromanager - wnpp
Microscopy Software
License: free
Svn
Version: 1.4.10-1

µManager is a software package for control of automated microscopes. It lets you execute common microscope image acquisition strategies such as time-lapses, multi-channel imaging, z-stacks, and combinations thereof. μManager works with microscopes from all four major manufacturers (Leica, Nikon, Olympus and Zeiss), most scientific-grade cameras and many peripherals (stages, filter wheels, shutters, etc.) used in microscope imaging (check the list of supported hardware). Since μManager runs as a plugin to ImageJ, image analysis routines are available within the application.

Unencumbered code provides a GUI for microscope image acquisition, a hardware interface layer and hardware interfacing for:

  • ASI stages, filter wheels and shutters
  • Arduino
  • Conix filter changer
  • Velleman K8055 and K8061 digital IO boards
  • Leica DMI microscopes
  • Ludl shutters, stages and filter Wheels
  • Nikon TE2000 microscope
  • Physik Instrumente stages
  • Pecon stage incubators
  • Prior shutters, stages and filter wheels
  • Spectral LMM5 laser controller
  • Sutter shutters, filter wheels and DG4
  • Vincent Uniblitz shutters
  • Yokogawa spinning disk confocal CSU22 and CSUX
  • Zeiss microscopes (two 'generations')
  • iidc1394 compatible cameras (through libdc1394)
Remark of Debian Med team: Partially problematic licenses

Unfortunately there is a pile of dirty licenses involved so I'm not sure this is ready for Debian yet. Some of the code cannot be given out and some drivers require kernel modules to be built. You have to sign NDAs to get access to all the code.

Mipav
quantitative analysis and visualization of medical images
License: non-free
Git
Version: 5.0.0.20100907-2

The MIPAV (Medical Image Processing, Analysis, and Visualization) application enables quantitative analysis and visualization of medical images of numerous modalities such as PET, MRI, CT, or microscopy. Using MIPAV's standard user-interface and analysis tools, researchers at remote sites can easily share research data and analyses, thereby enhancing their ability to research, diagnose, monitor, and treat medical disorders. MIPAV provides an interface for plug-ins and serves as the foundation for other projects (e.g. JIST).

This package provides downloader/installer for non-redistributable closed-source version of MIPAV and a convenience startup wrapper. You will have a choice of reviewing the license and accepting or declining it upon installation.

Mni-colin27-nifti
Talairach stereotaxic space template
License: free
Git
Version: 1.1-2

This template MRI volume was created from 27 T1-weighted MRI scans of a single individual that have been transformed into the Talairach stereotaxic space. The anatomical image is complemented by a brain and a head mask. All images are in 1x1x1 mm resolution.

This package provides the template in NIfTI format.

Openelectrophy - wnpp
data analysis GUI for intra- and extra-cellular recordings
License: free
Git
Version: 0.0.svn143

This package provides the startup script for the OpenElectrophy GUI.

Stabilitycalc
evaluate fMRI scanner stability
Responsible: NeuroDebian Team
License: BSD
Git
Language: Python

Command-line tools to calculate numerous fMRI scanner stability metrics, based on the FBIRN quality assurance test protocal. Any 4D volumetric timeseries image in NIfTI format is support input. Output is a rich HTML report.

Unofficial packages built by somebody else

Cdmedicpacs
web interface to PACS to access DICOM study images
License: GPL2

Web based PACS (Picture Archiving and Communication System) to access DICOM studies images, in an easy and quick manner.

  • Easy configuration of PACS nodes (AE,IP,Port) , status, statistics of storage form web interface.
  • Dynamic web page generation from DICOM data +- prospective preparation when system is idle.
  • Automatic video(mp4/gif) generation from Heart MRI at Patient’s heart bit frame rate and XA at 15 fps.
  • Still images in jpeg with Window/Level from DICOM header when present or with Histogram algorithm.
  • Possibility on large Studies of still images to make a single mp4 for Series instead of a bunch of jpeg.
  • Easy web deletion of Series/Studies and auto deletion (Study date/DB insertion) for temporal PACS.
  • Good DICOM interaction with Diagnostic Modalities and commercial DICOM Viewers/Work Stations.
  • Good DICOM interaction with free DICOM Viewers Aeskulap
Fiji
The Fiji image processing suite (based on ImageJ)
Responsible: Mark Longair
License: unknown

Fiji is a project aiming at simplifying:

  • the installation of ImageJ
  • the usage of ImageJ
  • the usage of specific, powerful ImageJ plugins
  • the development of plugins using ImageJ
Remark of Debian Med team: About packaging status the authors said:

See the thread on the Debian Med mailing list at: http://lists.debian.org/debian-med/2009/04/msg00059.html

  • We've been working to get rid of, or replace, any remaining non-DFSG licensed plugins, but there's at least one left. The bug for tracking this is here: http://pacific.mpi-cbg.de/cgi-bin/bugzilla/show_bug.cgi?id=19
  • At the moment Fiji depends on sun-java6 rather than openjdk.
  • The packages are rather large at the moment (about 35MiB). This is mostly due to bundling various components with Fiji that could be satisfied as dependencies in Debian, such as junit, jruby, etc. but I haven't had time to work on separating those out.
  • Fiji uses a modified version of ImageJA (which again is bundled into the fiji package) rather than depending on the imagej Debian package created by people on this list.
  • One of the aims of Fiji was to make Benjamin Schmid's Java3D-based 3D viewer plugin work out-of-the-box, since people often had trouble installing it manually. At the time when I first made these packages there were no java3d packages in Debian, but now that these are in sid we should eventually be able to switch to using those.
Mni-autoreg
MNI average brain (305 MRI) stereotaxic registration model
Responsible: NeuroDebian Team
License: no-free, but GPLed parts

This package provides a version of the MNI Average Brain (an average of 305 T1-weighted MRI scans, linearly transformed to Talairach space) specially adapted for use with the MNI Linear Registration Package.

  • average_305.mnc - a version of the average MRI that covers the whole brain (unlike the original Talairach atlas), sampled with 1mm cubic voxels
  • average_305_mask.mnc - a mask of the brain in average_305.mnc
  • average_305_headmask.mnc - another mask, required for nonlinear mode
Mni-n3
MNI Non-parametric Non-uniformity Normalization
Responsible: NeuroDebian Team
License: BSDish

MNI Non-parametric Non-uniformity Normalization (N3). This package provides the 'nu_correct' tool for unsupervised correction of radio frequency (RF) field inhomogenities in MR volumes. Two packages are provided:

  • mni-n3 - provides 'nu_correct'
  • libebtks-dev - MNI support library with numerical types and algorithms
Opendicom.net
API to DICOM in C# for Mono
Responsible: Albert Gnandt
License: LGPL

The openDICOM.NET project implements a new approach towards DICOM (Digital Imaging and Communications in Medicine) libraries. DICOM is a worldwide standard in Medical IT and is provided by the National Electrical Manufacturers Association (NEMA). This standard specifies the way medical images and meta data like study or patient related data is stored and communicated over different digital medias. Thus, DICOM is a binary protocol and data format.

The openDICOM# Class Library, main part of the openDICOM.NET project, provides an API to DICOM in C# for Mono and the .NET Framework. It is a completely new implementation of DICOM. In contrast to other similar libraries the intention of this implementation is to provide a clean classification with support of unidirectional DICOM data streaming. Another implemented goal is the support of DICOM as XML. This is not standard conform but very use- and powerful within software development, storage and manipulation. Currently, full read support of DICOM output stream and full write support to XML is supposed to be provided. The entire DICOM content can be accessed as sequence or as tree of class instances. Latter is the default representation of DICOM content by the library.

The openDICOM.NET Utils are a collection of console tools for working with the needed data dictionaries in different data formats (binary and textual), query of ACR-NEMA (prior DICOM standard) and DICOM files and transcoding them into image formats like JPEG and XML files. These utils are written in C# for Mono and the .NET Framework and are using the openDICOM# API for processing.

The openDICOM.NET Navigator recapitulates the openDICOM.NET Utils in form of a GTK# GUI. It provides different views with focus on DICOM data sets and visualization. Connectivity to GIMP is also given for single image processing purpose as well as the possibility to run through multi-frame images like a movie.

The openDICOM.NET Beagle Filter Plugin increases the usability of ACR-NEMA and DICOM query within your desktop. It makes DICOM content overall indexable for retrieval. The Beagle search engine relies on Mono/.NET and works in the background of your system, but is able to detect content changes in realtime (depending on your configuration).

All GUI applications focus the popular GNOME desktop, but are 100% platform independent by relying on Mono.

No known packages available but some record of interest (WNPP bug)

Devide - wnpp
Delft Visualization and Image processing Development Environment
Responsible: Mathieu Malaterre
License: BSD
Debian package not available

DeVIDE, or the Delft Visualization and Image processing Development Environment, is a Python-based dataflow application builder that enables the rapid prototyping of medical visualization and image processing applications via visual programming. In other words, by visually connecting functional blocks (think Yahoo pipes), you can create cool visualizations.

See the DeVIDE website at http://visualisation.tudelft.nl/Projects/DeVIDE

Dtitk - wnpp
DTI spatial normalization and atlas construction toolkit
License: GPL-3+
Debian package not available
Language: C++

DTI-TK is a spatial normalization & atlas construction toolkit, designed from ground up to support the manipulation of diffusion-tensor images (DTI) with special cares taken to respect the tensorial nature of the data. It implements a state-of-the-art registration algorithm that drives the alignment of white matter (WM) tracts by matching the orientation of the underlying fiber bundle at each voxel. The algorithm has been shown to both improve WM tract alignment and to enhance the power of statistical inference in clinical settings. The key features include:

  • NIfTI support for scalar, vector and DTI volumes
  • tool chains for manipulating DTI volumes: resampling, smoothing, warping, registration & visualization
  • pipelines for WM morphometry: spatial normalization & atlas construction for population-based studies
  • built-in cluster-computing support
  • interoperability with other major DTI tools: AFNI, Camino, DTIStudio & FSL
Please cite: H Zhang, P A Yushkevich, D C Alexander, and J C Gee: Deformable registration of diffusion tensor MR images with explicit orientation optimization. (2006)
Eeglab - wnpp
toolbox for processing and visualization of electrophysiological data
Responsible: NeuroDebian Team
License: GPL-2+
Debian package not available
Language: C, Matlab/Octave

EEGLAB is an interactive Matlab toolbox for processing continuous and event-related EEG, MEG and other electrophysiological data incorporating independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data.

Please register by following this link if you are using eeglab.
Please cite: Delorme A and Makeig S: EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics (2004)
Isis - wnpp
I/O framework for neuroimaging data
Responsible: NeuroDebian Team
License: GPL-2+
Debian package not available
Language: C++

This framework aids access of and conversion between various established neuro-imaging data formats, like Nifti, Analyze, DICOM and VISTA. ISIS is extensible with plugins to add support for additional data formats.

Jemris - wnpp
high performance computing MRI simulator
Responsible: NeuroDebian Team
License: GPL-2+
Debian package not available

JEMRIS, which stands for "Juelich Extensible MRI Simulator", is a general simulator of MRI (Magnetic Resonance Imaging) data. The general process of simulation consists of preparation by choice or implementation of sequence, sample and coil setup and the invocation of the simulation run itself.

Please cite: Tony Stöcker, Kaveh Vahedipour, Daniel Pflugfelder, N. Jon Shah: High-performance computing MRI simulations. (2010)
Opensourcepacs - wnpp
medical image referral, archiving, routing and viewing system
Responsible: Mathieu Malaterre
License: GPL
Debian package not available

OpenSourcePACS is a free, open source image referral, archiving, routing and viewing system. It adds functionality beyond conventional PACS by integrating wet read functions, implemented through DICOM Presentation State and Structured Reporting standards.

In its first release, OpenSourcePACS delivers a complete wet read system, enabling an imaging clinic or hospital to offer its services over the web to physicians within or outside the institution. In future releases, we hope to incorporate more RIS (dictation, transcription, and reporting) functionality.

OpenSourcePACS is a product of the UCLA Medical Imaging Informatics group (http://www.mii.ucla.edu/).

Visit - wnpp
visualization and graphical analysis tool for viewing scientific data
License: 3-clause BSD license with additional disclaimers
Debian package not available

VisIt is a free interactive parallel visualization and graphical analysis tool for viewing scientific data. Users can quickly generate visualizations from their data, animate them through time, manipulate them, and save the resulting images for presentations. VisIt contains a rich set of visualization features so that you can view your data in a variety of ways. It can be used to visualize scalar and vector fields defined on two- and three-dimensional (2D and 3D) structured and unstructured meshes.

VisIt was designed to handle very large data set sizes in the terascale range and yet can also handle small data sets in the kilobyte range.

Xnat - wnpp
platform for data management and productivity tasks in neuroimaging
License: XNAT SLA
Debian package not available
Language: java

The primary functionality of XNAT is to provide a place to store and control access to neuroimaging data. This includes sophisticated user control, search and retrieval, and archiving capabilities. As open-source software, XNAT also supports a wide variety of research-based processing pipelines, and is able to link up with supercomputer processing power to dramatically shorten image processing time.

Please register by following this link if you are using xnat.
Please cite: Marcus, D.S., Olsen T., Ramaratnam M., and Buckner, R.L.: The Extensible Neuroimaging Archive Toolkit (XNAT): An informatics platform for managing, exploring, and sharing neuroimaging data. (2007)

No known packages available

Blox
medical imaging and visualization program
License: GPL
Debian package not available

The purpose of the project is to develop a quantitative medical imaging and visualization program for use on brain MR, DTI and MRS data. It is a joint project of the Kennedy Krieger Institute and the Johns Hopkins University, Psychiatric Neuroimaging Lab (http://pni.med.jhu.edu/methods/morph.htm).

Brainvisa
image processing factory for MR images
License: Free? (CeCill License)
Debian package not available

BrainVISA is a software, which embodies an image processing factory. A simple control panel allows the user to trigger some sequences of treatments on series of images. These treatments are performed by calls to command lines provided by different laboratories. These command lines, hence, are the building blocks on which are built the assembly lines of the factory. BrainVISA is distributed with a toolbox of building blocks dedicated to the segmentation of T1-weighted MR images. The product of the main assembly line made up from this toolbox is the following: grey/white classification for Voxel Based Morphometry, Meshes of each hemisphere surface for visualization purpose, Spherical meshes of each hemisphere white matter surface, a graph of the cortical folds, a labeling of the cortical folds according to a nomenclature of the main sulci.

Dcm4chee
Clinical Image and Object Management (enterprise)
License: LGPL, MPL, Apache, other (also non-free)
Debian package not available

Contained within the dcm4che project is dcm4chee (the extra 'e' stands for 'enterprise'). dcm4chee is an Image Manager/Image Archive (according to IHE). The application contains the DICOM, HL7 services and interfaces that are required to provide storage, retrieval, and workflow to a healthcare environment. dcm4chee is pre-packaged and deployed within the JBoss application server. By taking advantage of many JBoss features (JMS, EJB, Servlet Engine, etc.), and assuming the role of several IHE actors for the sake of interoperability, the application provides many robust and scalable services.

Dicom4j
Java framework for Dicom
License: GPL
Debian package not available

Java framework for Dicom

Drjekyll
interactive voxel editor for viewing and editing three-dimensional images
License: GPL
Debian package not available

It is specifically aimed at postprocessing of segmented datasets, but offers some functionality for raw data as well. Voxel elements (=voxels) and pixel ("picture element") are viewed as data sets and can be processed by this program as kind of a final polishing process.

Dti-query
dynamic queries of the white matter brain pathways
License: MIT
Debian package not available
Language: C++

This application allows neuroscientists to place and interactively manipulate box-shaped regions (or volumes of interest) to selectively display pathways that pass through specific anatomical areas. A simple and extensible query language allows for arbitrary combinations of these queries using Boolean logic operators. Queries can be further restricted by numerical path properties such as length, mean fractional anisotropy, and mean curvature.

Remark of Debian Med team: Depends on RAPID library that is available under non-commercial

licensing terms.

Ecg2png
convert scanned electrocardiograms into PNG format
License: GPL
Debian package not available

This program is designed to convert scanned 12-lead electrocardiograms into PNG format and a web-friendly image size. It assumes that the electrocardiogram (ECG) is printed with a black line on white paper with a red grid.

The problems this program is designed to solve are (1) an ECG scanned at relatively high resolution (300 to 600 dots per inch) imposes a substantial load on the web browser because it contains about 6 million pixels which may require 18 to 24 MB of RAM to store for display. Also, (2) typical scanners convert a clean paper ECG into a multitude of colors, include green and blue. The resulting file cannot be compressed efficiently because it does not contain as much redundancy, and thus takes more time to transmit over low-speed network connections.

Remark of Debian Med team: Homepage vanished

The homepage of this project that used to be at http://www.cardiothink.com/downloads/ecg2png/ vanished but the source can be downloaded fro instance from http://www.freshports.org/graphics/ecg2png/ .

Gimias
Graphical Interface for Medical Image Analysis and Simulation
License: BSD-like
Debian package not available

GIMIAS is a workflow-oriented environment for solving advanced biomedical image computing and individualized simulation problems, which is extensible through the development of problem-specific plug-ins. In addition, GIMIAS provides an open source framework for efficient development of research and clinical software prototypes integrating contributions from the Physiome community while allowing business-friendly technology transfer and commercial product development.

Hid
database management system for clinical imaging
License: BSD, BIRN
Debian package not available
Language: java

The Human Imaging Database (HID) is an extensible database management system developed to handle the increasingly large and diverse datasets collected as part of the MBIRN and FBIRN collaboratories and throughout clinical imaging communities at large.

Please register by following this link if you are using hid.
Please cite: Keator, D.B.; Grethe, J.S.; Marcus, D.; Ozyurt, B.; Gadde, S.; Murphy, S.; Pieper, S.; Greve, D.;Notestine, R.; Bockholt, H.J.; Papadopoulos, P.: A National Human Neuroimaging Collaboratory Enabled By The Biomedical Informatics Research Network (BIRN) (2008)
Maris
package suite for Radiological Workflow
License: GPL
Debian package not available

The MARiS Project goal is to realize a package suite for Radiological Workflow using Open Source tools and technologies in according with IHE guidelines. The architecture of the single packages is based on the concept of IHE actor: this is very useful to develop a system that is an ensemble of single pieces that cooperate together using IHE profiles.

Medisnap
photograph, manage, view, compare, document and archive medical photos
License: GPL-3
Debian package not available

Photograph, manage, view, compare, document and archive medical photos fully integrated into doctor's practice systems. Take a photo and immediately see how the picture gets archived to your current patient automatically.

  • direct support for Olympus E-System cameras
  • network support
  • fully integrated via GDT interface into many medical software systems
  • organise photos by patients effectively
  • define your own localisations
  • compare photos of healing processes at different times
  • work time-optimized and effective, photos automatically get added and archived under the current patient in your system
  • easily print selected photos and archive or give them to your patients
Mesa-test-tools
IHE Test Software for Radiology
License: free
Debian package not available

The MESA software release which is available at http://ihedoc.wustl.edu/mesasoftware/10.15.0/dist/ provides several tools that might cover a wide range of applications for Integrating the Healthcare Enterprise (IHE) testing.

Another important element of the IHE testing process is the set of software tools HIMSS and RSNA have commissioned. Developed by the Electronic Radiology Laboratory at the Mallinckrodt Institute of Radiology, Washington University of St. Louis, the MESA tools are designed for use by participating companies in implementing IHE capabilities in their systems and preparing for the Connectathon. Their purpose is to provide communication partners, test data and test plans to allow organizations to provide a baseline level of testing as they implement the IHE Technical Framework. These tools are made available to participants during the period of an IHE demonstration year and are then released into the public domain at the end of that cycle. The latest version of the MESA Test Tools available in the public domain can be found here.

This kind of software is definitively valuable for information systems vendors and imaging systems vendors.

Because the CTN Debian package is based on an upstream dead project these tools should have a high priority for packaging because the CTN homepage http://erl.wustl.edu/research/dicom/ctn.html says: "The CTN software is also embedded within the MESA tools. The version of CTN software in those tools does not have a separate release number but is more current than version 3.0.6."

Miview
Medical Images viewer and converter
License: GPL-3+
Debian package not available
Language: C++

MIView features - DICOM files browser - volume rendering - reads DICOM v3, NEMA/ACR, Papyrus, Jpeg, GIF, bitmap, TIFF,

  Analyze 7.5, and Nifti1 files
- can convert to raster (jpeg, bitmap, etc) and Analyze/Nifti1
Remark of Debian Med team: At the moment available only for Windows, but author says

there should be no major showstoppers to build it on Linux -- just needs building infrastructure

Mni-icbm152-nlin-2009
MNI stereotaxic space human brain template
Responsible: NeuroDebian Team
License: custom, DFSG-compliant
Debian package not available

This is an unbiased standard magnetic resonance imaging template volume for the normal human population. It has been created by the Montreal Neurological Institute (MNI) using anatomical data from the International Consortium for Brain Mapping (ICBM).

The package provides a 1x1x1 mm and 0.5x0.5x0.5 mm resolution templates (hemissphere-symetric and asymetric non-linearily co-registered versions), some including T1w, T2w, PDw modalities, T2 relaxometry, and tissue probability maps. In addition, it contains a lobe atlas, and masks for brain, eyes and face.

Please cite: V.S. Fonov, A.C. Evans, R.C. McKinstry, C.R. Almli and D.L. Collins: Unbiased nonlinear average age-appropriate brain templates from birth to adulthood. (2009)
Remark of Debian Med team: This package is waiting for the Debian data package archive to become available.
Mrisim
simulator for magnetic resonance imaging data
Responsible: NeuroDebian Team
License: BSD-like
Debian package not available

mrisim is a simple Magnetic Resonance Imaging (MRI) simulation program which produces MINC volumes from a segmented and labelled brain phantom. It allows intrinsic tissue parameters (T1, T2...) and pulse sequence parameters (TR, TE ...) to be specified and then produces simulated images with noise. Currently, no artifacts are implemented.

Omero
coming standard LIMS for microscopy images
License: GPL
Debian package not available

OMERO is client-server software for visualisation, management and analysis of biological microscope images.

Piano
medical image processing library for surgical planning
License: BSD
Debian package not available

Piano is a library containing roughly 75 algorithms and tools for multi-dimensional medical image processing, analysis and visualization. It is used in the field of surgical planning.

Pymeg
suite for analysis of magnetoencephalography (MEG) data
License: GPL-3
Debian package not available
Language: Python
 PyMEG is a project in Python to do various neuroimaging processing
 with magnetoencephalography (MEG) data. The purpose of this project,
 is to create a suite of functions to do MEG analysis in Python.
Remark of Debian Med team: Needs DFSG-ification.
       According to the author is not yet ready for the use by
       mortals -- wasn't released yet.
Stir
Software for Tomographic Image Reconstruction
License: GPL
Debian package not available

STIR is Open Source software for use in tomographic imaging. Its aim is to provide a Multi-Platform Object-Oriented framework for all data manipulations in tomographic imaging. Currently, the emphasis is on (iterative) image reconstruction in PET, but other application areas and imaging modalities can and might be added.

STIR is the successor of the PARAPET software library which was the result of a (European Union funded) collaboration between 6 different partners, the PARAPET project..

Remark of Debian Med team: Even if this is GPLed software the download requires registration.
Tempo
3D visualization of brain electrical activity
License: BSD
Debian package not available
Language: C++, Qt

TEMPO is open source software for 3D visualization of brain electrical activity. TEMPO accepts EEG file in standard EDF format and creates animated sequence of topographic maps. Topographic maps are generated over 3D head model and user is able to navigate around head and examine maps from different viewpoints. Most mapping parameters are adjustable through appropriate graphical user interface controls. Also, individual topographic maps could be saved in PNG format for future examination or publishing.

Remark of Debian Med team: Packaged for OpenSuSE http://en.opensuse.org/TEMPO
*Popularitycontest results: number of people who use this package regularly (number of people who upgraded this package recently) out of 170477